Laser Therapy and Photobiomodulation Research Studies

Explore the growing range of research studies on laser and photobiomodulation therapies and their uses and effectiveness:

Additional Research References:

Transcranial Photobiomodulation (PBM) Therapy With Laser or LED Studies To Treat CNS Disorders In Humans

Lampl et al., 2007 (Stroke). Transcranial NIR laser therapy to treat acute ischemic stroke, NeuroThera, NEST-1 study
Zivin et al., 2009 (Stroke). Effectiveness and safety, transcranial NIR laser therapy to treat acute ischemic stroke (NEST study)
Schiffer et al., 2009 (Behav Brain Funct). Transcranial, NIR LED treatment for major depression and anxiety
Naeser & Hamblin, 2011 (Editorial, PMLS). Potential for transcranial laser or LED therapy to treat stroke, TBI and neurodegenerative disease
Naeser, Saltmarche et al., 2011 (PMLS): Transcranial LED to improve cognition in TBI and PTSD, with home treatment (2 case reports)
Whelan et al., 2012 (Front. In Bio.). Therapeutic effect of near infrared (NIR) light on Parkinson’s disease models
Nawashiro et al., 2012 (PMLS). Focal increase in cerebral blood flow after transcranial, NIR LED to forehead in severe, chronic TBI (persistent vegetative state)
Gonzalez-Lima et al., 2013 (Neuroscience). Transcranial Infrared Laser Stimulation Produces Beneficial Cognitive and Emotional Effects in Humans
Naeser, Zafonte et al., 2014 (J of Neurotrauma). Significant improvement in cognition post- 18 transcranial LED treatments in chronic, TBI
Saltmarche, Naeser et al., 2017 (PMLS). Significant improvement in cognition in 5 chronic, dementia patients post- 12 weeks, transcranial plus intranasal NIR LED treatments

Laser Acupuncture Research by Margaret Naeser, Ph.D., L.Ac., Dipl.Ac. (NCCAOM):

Naeser, 2000 (Lecture at Rehab Inst. Of Chicago). Acupuncture and Laser Acupuncture to Treat Paralysis in Stroke, Research with Neuroimaging, and When to Refer a Patient
Naeser et al., 1995 (AJA). Laser Acupuncture In the Treatment of Paralysis In Stroke Patients: A CT Scan Lesion Site Study
Naeser, 1997 (JACM). Neurological Rehabilitation: Acupuncture and Laser Acupuncture to Treat Paralysis in Stroke, Other Paralytic Conditions, and Pain in Carpal Tunnel Syndrome
Naeser et al., 2002 (APMR). Carpal Tunnel Syndrome Pain Treated With Low-Level Laser and Microamperes Transcutaneous Electric Nerve Stimulation: A Controlled Study
Naeser et al., 1999 (JACM). Carpal Tunnel Syndrome: Clinical Outcome After Low-Level Laser Acupuncture, Microamps Transcutaneous Electrical Nerve Stimulation, and Other Alternative Therapies – An Open Protocol Study
Naeser et al., 1999 (JACM). Review of Second Congress, World Association for Laser Therapy (WALT) Meeting
Schlager et al., 1998 (BJA). Laser Stimulation of Acupuncture Point P6 Reduces Postoperative Vomiting in Children Undergoing Strabismus Surgery
Neuman et al., 1997 (AAI). Narrow-Band Red Light Phototherapy in Perennial Allergic Rhinitis and Nasal Polyposis
Litscher et al., 2005 (Pabst Science Publishers). Collection of studies in laser acupuncture published in this clinical manual – Laserneedle Acupuncture: Science and Practice
Kahn J, 1985 (JOSPT). Case Reports: Open Wound Management with the HeNe (6328 AU) Cold Laser
Kleinkort et al., 1984 (AJA). Laser Acupuncture: Its Use in Physical Therapy
Walker, 1983 (Neuroscience Letters). Relief Chronic Pain by Low Level Power Laser Irradiation
Yinchun, 1992 (IJCA). Puncture of Quchi with He-Ne Laser in the Treatment of Papular Urticaria
Basford, 1989 (CRPRM). The Clinical and Experimental Status of Low Energy Laser Therapy
Yunkui et al., 1987 (JTCM). A Study of The Treatment Schizophrenia With He-Le Laser Irradiation of Acupoint
Zuoze et al., 1986 (JTCM). Therapeutic Effect of He-Le Laser Irradiation of Point Erman in Schizophrenic Auditory Hallucination – A Clinical Assessment
Guangzhi, 1989 (JTCM). Treatment of Pain Laser Irradiation – A Report of 76 Cases
Shaoqin et al., 1990 (JTCM). Treatment of Allergic Rhinitis With Helium Neon Laser on Acupoints

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